Chapter 1.26: Pharmacological Principles of Diet (Atreyabhadrakapyiya Adhyaya / आत्रेयभद्रकाप्यीय अध्याय)
Foundational pharmacology chapter establishing the six tastes (rasa), their elemental composition, potency (veerya), post-digestive effect (vipaka), specific potency (prabhava), and the doctrine of incompatible food combinations (viruddha ahara).
Source: Astanga Hridaya Sutrasthan by Vagbhata
This foundational pharmacological chapter establishes the mechanisms governing therapeutic substance action through six tastes, their elemental composition, potency, post-digestive transformation, and specific potency. The doctrine of incompatible food combinations (viruddha ahara) identifies potentially fatal combinations like fish with milk or honey with hot water. The chapter provides a framework for predicting beneficial versus harmful effects based on multi-factorial drug action principles.